Biomechanical Effects of Hindfoot Alignment in Supination External Rotation Malleolar Fractures: A Human Cadaveric Model.

BACKGROUND: Pressure distribution in the ankle joint is known to be dependent on various factors, including hindfoot alignment. We seek to evaluate how hindfoot alignment affects contact pressures in the ankle joint in the setting of supination external rotation (SER) type ankle fractures. METHODS: SER fractures were created in 10 human cadaver lower extremity specimens, simulating progressive stages of injury: without fracture (step 0), SER fracture and intact deltoid ligament (step 1), superficial deltoid ligament disruption (step 2), and deep deltoid ligament disruption (step 3). At each step, varus and valgus alignment was simulated by displacing the calcaneal tuberosity 7 mm medial or lateral. Each limb was axially loaded following each osteotomy at a static load of 350 N. The center of force (COF), contact area (CA), and peak contact pressure (PP) under load were measured, and radiographs of the ankle mortise were taken to analyze the medial clear space (MCS) and talar tilt (TT). RESULTS: The COF (5.3 mm, P = .030) and the CA (-188.4 mm2, P = .015) changed in step 3 in the valgus hindfoot alignment compared to baseline parameters, indicating the importance of deep deltoid ligament integrity in maintaining normal ankle joint contact stress in the valgus hindfoot. These changes were not seen in the setting of varus alignment (COF: 2.3 mm, P = .059; CA -121 mm2, P = .133). PP were found to not change significantly in either varus or valgus (varus: -4.9 N, P = .132; valgus: -4 N, P = .464).The MCS demonstrated widening in step 3 compared to step 2 (0.7 mm, P = .020) in both varus and valgus hindfoot. The TT increased significantly in step 3 in the valgus hindfoot (2.8 degrees, P = .020) compared to step 0. CONCLUSION: SER-IV fractures with valgus hindfoot alignment showed significant changes in pressure distribution and radiographic parameters when compared to SER-IV fractures with varus hindfoot alignment. CLINICAL RELEVANCE: Based on this cadaver modeling study, patients with SERIV fracture with varus hindfoot alignment and complete deltoid ligament lesion may not need fracture fixation, whereas those with valgus hindfoot alignment likely need fracture fixation.

[Foot and ankle pathologies during pregnancy]. / Pathologies du pied et de la cheville pendant la grossesse.

Foot and ankle pain and oedema are a common complaint among pregnant women. A range of hormonal and anatomical changes during pregnancy can cause modifications in foot and ankle's biomechanics and anatomy. The main foot and ankle pathologies encountered in pregnancy are progressive collapsing foot deformity, plantar fasciitis, heel pain, oedema, and fractures. Workup includes the use of radiological evaluation that could pose a risk to the fetus, depending on the gestational age. Treatment plans range from symptomatic conservative to surgical options and a multidisciplinary approach is often recommended and warranted. Our paper aims to present these different pathologies and propose a structured treatment plan to address them.

La douleur et l'œdème du pied et de la cheville sont fréquents chez les femmes enceintes. Plusieurs changements hormonaux et anatomiques pendant la grossesse entraînent des modifications dans la biomécanique et l'anatomie du pied et de la cheville. Les pathologies les plus fréquentes concernant cette localisation rencontrées pendant la grossesse sont le pied plat progressif, la fasciite plantaire, la douleur au talon, l'œdème et les fractures. Le bilan demande souvent une évaluation radiologique pouvant présenter un risque pour le fœtus, en fonction de l'âge gestationnel. Les plans de traitement vont du traitement conservateur à la chirurgie et une approche multidisciplinaire est souvent recommandée et justifiée. Cet article présente ces différentes pathologies et propose un plan de traitement structuré.

Accuracy of a Patient-Specific Total Ankle Arthroplasty Instrumentation.

BACKGROUND: Total ankle arthroplasty (TAA) is a preferred surgical option for end-stage ankle osteoarthritis; however, it is a demanding procedure with a higher historical rate of revision compared with ankle fusion. Patient-specific instrumentation (PSI) has been introduced to optimize prosthesis alignment and theoretically overall improve TAA outcomes. The goal of this study is to report on the experience and surgical outcomes of one implant with specific evaluation of the accuracy and reproducibility of the system with respect to prosthesis alignment and prediction of implant size. METHODS: A retrospective, multicentered study involving 4 foot and ankle fellowship-trained orthopaedic surgeon's patients undergoing TAA between January 1, 2015, and December 31, 2018, using the PROPHECY PSI system. RESULTS: 80 TAA procedures were performed. On average the postoperative tibial component alignment was 89.9 (range, 86.1-96.5) degrees in the coronal plane, with a mean sagittal alignment of 88.1 (range, 81.3-96.7) degrees. The mean deviation from neutral sagittal alignment improved from 4.9 ± 3.9 degrees preoperatively to 2.7 ± 1.7 degrees postoperatively, whereas the mean coronal alignment improved from 3.3 ± 2.5 degrees to 1.3 ± 1.1 degrees. The PSI software correctly determined the tibial implant size in 70 patients (89%). Prediction of talar implant sizing was less accurate than the tibial component, with 56 patients (71%) using the predicted sized implant. The overall implant survival at a mean follow-up of 45 months (range, 27-76) was 97.5%. CONCLUSION: We found that this PSI system accurately and reliably assisted in implant total ankle prosthesis positioning within a clinically acceptable margin and without significant outliers. Prediction of implant size was not as accurate as component orientation. LEVEL OF EVIDENCE: Level III, retrospective study.

[Malleolar Fractures - Indication for Nonoperative and Operative Treatment]. / Malleolarfrakturen.

Malleolar Fractures - Indication for Nonoperative and Operative Treatment Abstract. In order to understand the trauma mechanism and the expected pattern of injury, malleolar fractures can be classified according to Lauge-Hansen [1]. For isolated lateral malleolar fractures, the Weber classification is also frequently used [2]. For most Weber A fractures and 80% of Weber B fractures conservative treatment is indicated. In all isolated Weber B fractures a supination-external rotation (SER) injury has to be distinguished from a pronation-abduction (PA) injury according to the Lauge-Hansen classification. In SER fractures, stability should be assessed by a gravity stress and a weightbearing radiograph. If the fracture is stable, it can be treated nonoperatively. We recommend surgical treatment for unstable Weber B SER injuries, Weber B PA injuries, and Weber C fractures.

Ankle Joint Pressure in Supination-External Rotation Injuries: A Biomechanical Study in an Unrestrained Cadaver Model.

BACKGROUND: Previous biomechanical studies simulating supination-external rotation (SER) IV injuries revealed different alterations in contact area and peak pressure. We investigated joint reaction forces and radiographic parameters in an unrestrained, more physiological setup. METHODS: Twelve lower leg specimens were destabilized stepwise by osteotomy of the fibula (SER II) and transection of the superficial (SER IVa) and the deep deltoid ligament (SER IVb) according to the Lauge-Hansen classification. Sensors in the ankle joint recorded tibio-talar pressure changes with axial loading at 700 N in neutral position, 10° of dorsiflexion, and 20° of plantarflexion. Radiographs were taken for each step. RESULTS: Three of 12 specimen collapsed during SER IVb. In the neutral position, the peak pressure and contact area changed insignificantly from 2.6 ± 0.5 mPa (baseline) to 3.0 ± 1.4 mPa (SER IVb) (P = .35) and from 810 ± 42 mm2 to 735 ± 27 mm2 (P = .08), respectively. The corresponding medial clear space (MCS) increased significantly from 2.5 ± 0.4 mm (baseline) to 3.9 ± 1.1 mm (SER IVb) (P = .028).The position of the ankle joint had a decisive effect on contact area (P = .00), center of force (P = .00) and MCS (P = .01). CONCLUSION: Simulated SER IVb injuries demonstrated radiological, but no biomechanical changes. This should be considered for surgical decision making based on MCS width on weightbearing radiographs. LEVELS OF EVIDENCE: Not applicable. Biomechanical study.

Atopic dermatitis in the COVID-19 era: Results from a web-based survey.

Given that the COVID-19 era has changed the behavior of all individuals, and since previous reports about its possible impact on atopic dermatitis (AD) patients remained speculative, in this survey we aimed to explore the real impact of COVID-19 among AD patients. All participants provided verbal consent prior to completing the survey. A 37-question web-based survey with no personal identifiers was sent to 212 previously identified AD patients. Itching, sleep disturbances, SARS-CoV-2, illness cost, economic dependence, monthly income, and monthly investment in AD before and during the pandemic, were all included in the analysis. A response rate of 73.1% was obtained. The mean age of participants was 30 years-old, and 57% were women. Around 75% reported AD worsening, and 59.4% of the patients reported sleep problems. Uncertainty, anxiety, and pessimism were frequent during the pandemic. Only 1.3% tested positive for SARS-CoV-2, and it was only significantly associated with comorbidities (p=0.03; Chi2 Test). A significant difference was found in economic dependence and monthly income when compared between before and during the pandemic. This study provides probably the best possible assessment of the clinical, social, and economic effects of the pandemic on patients with an already proven diagnosis of AD.

Recurrence Rate After Wide Resection of Plantar Fibromatosis: A Case Series and Systematic Literature Review.

BACKGROUND: The aim was to assess the recurrence rate and clinical outcome after wide resection for plantar fibromatosis. METHODS: A total of 12 patients, 2 to 13 years after wide resection, were assessed for local and magnetic resonance imaging tomographic signs of recurrence at the clinical follow-up. In addition, a systematic review of the literature was conducted. RESULTS: After 7.8 years (2-13), 2 patients (17%) suffered a recurrence. At the last follow-up, median Foot Functional Index was 1 (0-66) and American Orthopaedic Foot and Ankle Society score was 95 (44-100). Six studies with 109 feet (92 patients) were included in the systematic review. The recurrence rate depends on the width of the resection: 67% after local resection, 42% after wide resection, and 27% after fasciectomy. CONCLUSION: In patients with symptomatic plantar fibromatosis, we recommend a wide resection or fasciectomy over a local resection because of the inferior recurrence rate. LEVELS OF EVIDENCE: Level IV: Retrospective case series.

Radiological and biomechanical assessment of displaced greater tuberosity fractures.

PURPOSE: Greater tuberosity fractures are challenging lesions concerning decision-making. In order to improve our treatment algorithm, we developed a new method, which allows predicting a possible subacromial conflict on standard anteroposterior radiographs, considering not only the displacement of the fragment but also the width of the subacromial space. METHODS: The measurement technique consisted of drawing three concentric circles on true anteroposterior radiographs. The inner circle (radius Rh) perfectly matched the humeral head surface. The medial circle (radius Rt) was tangent to the greater tuberosity, and the outer circle (radius Ra) touched the undersurface of the acromion. The ratio Rt/Rh, which describes how much the greater tuberosity projects above the articular surface, and the relationship (Rt-Rh)/(Ra-Rh), which quantifies the space occupied by the greater tuberosity under the acromion, were calculated and called Greater Tuberosity Index and Impingement Index, respectively. Five dry humeri were used to assess the influence of rotation and abduction on the Greater Tuberosity Index. The radiographs of 80 shoulders without any osseous pathology were analyzed to obtain reference values for both indices. Finally, greater tuberosity fractures with different displacements were created in five cadaver specimens, and subacromial impingement was correlated with these parameters. RESULTS: On anteroposterior radiographs, the greater tuberosity was most prominent in neutral rotation, regardless of abduction. In shoulders without osseous pathology, the Greater Tuberosity Index and the Impingement Index averaged 1.15 (range 1.06-1.28) and 0.46 (range 0.21-0.67). In the biomechanical experiments, the Impingement Index was a better discriminator for subacromial impingement than the Greater Tuberosity Index. A fracture with a displacement corresponding to an Impingement Index of 0.71 or greater was associated with subacromial impingement. CONCLUSIONS: Reduction of a displaced greater tuberosity fragment should be considered if the Impingement Index is 0.7 or greater. The measurement method is simple and reliable and has the potential to be used for the assessment of subacromial impingement in other conditions.

Malalignment and Lateral Ankle Instability: Causes of Failure from the Varus Tibia to the Cavovarus Foot.

A lower leg or hindfoot varus malalignment is a frequently encountered but underestimated cause of chronic ankle instability and ankle arthritis in the long term. When evaluating patients with ankle instability, a high index of clinical suspicion for tibia and hindfoot malalignment and subsequent biomechanics should be maintained. Management of lateral ankle instability in the presence of varus malalignment must comprise a generous indication for accurate hindfoot realignment. In young and active patients, realignment should be combined with formal lateral ligamentous repair.

Weightbearing vs Gravity Stress Radiographs for Stability Evaluation of Supination-External Rotation Fractures of the Ankle.

BACKGROUND: Isolated lateral malleolar fractures may result from a supination-external rotation (SER) injury of the ankle. Stable fractures maintain tibiotalar congruence due to competent medial restraints and can be treated nonoperatively with excellent functional results and long-term prognosis. Stability might be assessed with either stress radiographs or weightbearing radiographs. METHODS: A consecutive series of patients with closed SER fractures (presumed AO 44-B1) were prospectively enrolled from 2008 to 2015. Patients with clearly unstable fractures (medial clear space more than 7 mm) on the initial nonweightbearing radiograph were excluded and operated on. All other patients were examined with a gravity stress and a weightbearing anteroposterior radiograph. Borderline instability of the fracture was assumed when the medial clear space was 4 to 7 mm. Those were treated nonoperatively. RESULTS: Of 104 patients with isolated lateral malleolar fractures of the SER type, 14 patients were treated operatively because of clear instability (displacement) on the initial radiographs. Of the nonoperative patients, 44 patients demonstrated borderline instability on the gravity stress but stability on the weightbearing radiograph ("gravity borderline"); the remaining 46 were stable in both tests ("gravity stable"). At an average follow-up of 23 months, no significant differences were seen in the American Orthopaedic Foot & Ankle Society hindfoot score (92 points gravity-borderline group vs 93 points gravity-unstable group), the Foot Functional Index score (11 vs 10 points), the Short Form 36 (SF-36) physical component (86 vs 85 points), and SF-36 mental component (84 vs 81 points). Radiographically, all fractures had healed with anatomic congruity of the ankle. CONCLUSION: Weightbearing radiographs provided a reliable basis to decide about stability and nonoperative treatment in isolated lateral malleolar fractures of the SER type with excellent clinical and radiographic outcome at short-term follow-up. Gravity stress radiographs appear to overrate the need for operative treatment. LEVEL OF EVIDENCE: Level III, prospective comparative study.

Caracterización socioeconómica, geográfica y laboral de los médicos dermatólogos en Colombia / Social, economic, geographic and occupational characterization of dermatologists in Colombia

El Sistema General de Seguridad Social en Salud de Colombia ha repercutido profundamente en la forma como se prestan los servicios de salud, incluyendo las condiciones laborales de los trabajadores del sector salud. El mercado laboral del sector salud sufrió modificaciones importantes que incluyen el cambio en los aspectos relacionados con la contratación, los salarios y las condiciones de trabajo de los profesionales. Con el presente estudio se pretende hacer una descripción o aproximación de la situación socioeconómica, geográfica y laboral de los dermatólogos en Colombia Este es un estudio descriptivo que se llevó a cabo entre febrero y agosto del 2011, de los dermatólogos adscritos a la Asociación Colombiana de Dermatología y Cirugía Dermatológica (Asocolderma) y los residentes de Dermatología, en el que se obtuvieron datos socioeconómicos, laborales y geográficos, entre ellos la distribución etaria y por sexo, así como las ciudades con mayor presencia laboral de dermatólogos, el régimen del sistema en que se desempeñan y el tipo de contratación en la que se desenvuelven. Esta recopilación de datos, de la cual no hay antecedentes en el país, constituye la muestra más grande que se analizado hasta la fecha para determinar la caracterización social, demográfica e incluso económica de los dermatólogos en Colombia, y este estudio servirá de base para la adecuada toma de decisiones en las diferentes esferas que enmarcan el estudio y ejercicio de la Dermatología en nuestro país.

Guías colombianas para el manejo del acné: una revisión basada en la evidencia por el Grupo Colombiano de Estudio en Acné

El acné es una enfermedad inflamatoria crónica que afecta, principalmente, adolescentes y adultos jóvenes. Se calcula que antes de los 21 años entre el 80 y el 90% de esta población ha estado expuesta a la enfermedad. Sin embargo, el acné puede persistir después de los 21 años y se sabe que 12% de las mujeres mayores de 25 años aún sufren de acné facial. El arsenal terapéutico para el acné consta de medicamentos tópicos y sistémicos que han demostrado su eficacia en la reducción de las lesiones. El mecanismo de acción de estos medicamentos está orientado, al menos, a uno de los cuatro factores fisiopatológicos reconocidos como responsables de la formación de las lesiones del acné, a saber: trastornos de la queratinización, hipersecreción sebácea, proliferación de Propionibacterium acnes o actividad inflamatoria in situ. La elección del tratamiento apropiado depende de varios factores, como la forma clínica de la enfermedad (de retención o inflamatoria), la gravedad de la misma y la respuesta del paciente a tratamientos previos. Asimismo, y entendiendo al acné como una enfermedad de carácter crónico, el tratamiento debe incluir una fase inicial con el objetivo de lograr una mayor reducción de la extensión y gravedad de las lesiones, y una fase de mantenimiento orientada a la prevención de las recaídas o exacerbaciones. Además, el resultado del tratamiento depende del cumplimiento del mismo y para lograrlo, es fundamental una adecuada relación médico-paciente. Este documento presenta el resultado de una revisión actualizada de la literatura, que incluye guías nacionales e internacionales para el manejo del acné y formula recomendaciones terapéuticas basadas en el mejor nivel de “evidencia” que se encontró. Su implementación permitirá la unificación de criterios con el objetivo de ofrecer un mejor manejo a los pacientes con la enfermedad, evitando así sus secuelas físicas y emocionales. Por otro lado, las guías presentan un marco científico y conceptual con la suficiente validez para su inclusión en los protocolos del plan obligatorio de salud.

Nódulo de Villar: presentación de un caso / Villar’s nodule: case report

La endometriosis es la presencia de endometrio por fuera de la cavidad uterina, siendo el sitio más frecuente la cavidad pélvica. Afecta al 8%-15% de las mujeres en edad fértil, y produce complicaciones ginecológicas importantes. La localización en la piel ocurre en el 1% de los casos, la mayoría sobre cicatrices quirúrgicas abdominales o perineales. Son mucho más raros los casos de endometriosis cutánea primaria, por lo cual presentamos el de esta paciente.